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“Calcium bombs” as harbingers of synaptic pathology and their mitigation by magnesium at murine neuromuscular junctions
Excitotoxicity is thought to be an important factor in the onset and progression of amyotrophic lateral sclerosis (ALS). Evidence from human and animal studies also indicates that early signs of ALS include degeneration of motor nerve terminals at neuromuscular junctions (NMJs), before degeneration...
Autores principales: | Dissanayake, Kosala N., Redman, Robert R., Mackenzie, Harry, Eddleston, Michael, Ribchester, Richard R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361872/ https://www.ncbi.nlm.nih.gov/pubmed/35959105 http://dx.doi.org/10.3389/fnmol.2022.937974 |
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