Synthesis and biological activity, and molecular modelling studies of potent cytotoxic podophyllotoxin-naphthoquinone compounds

A new approach for the synthesis of podophyllotoxin-naphthoquinone compounds using microwave-assisted three-component reactions is reported in this study. Novel podophyllotoxin-naphthoquinone derivatives with modification on ring E were synthesized. All the synthetic compounds were assessed in terms...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha Thanh, Nguyen Thi, Quynh Giang, Nguyen Thi, Thu Ha, Thi, Phuong Hoang, Le-Nhat-Thuy, Giang, Dang Thi, Tuyet Anh, Le-Quang, Bao, Pham-The, Hai, Van Nguyen, Tuyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361925/
https://www.ncbi.nlm.nih.gov/pubmed/36043070
http://dx.doi.org/10.1039/d2ra03312g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361925/
https://www.ncbi.nlm.nih.gov/pubmed/36043070
http://dx.doi.org/10.1039/d2ra03312g

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