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Synthesis and biological activity, and molecular modelling studies of potent cytotoxic podophyllotoxin-naphthoquinone compounds
A new approach for the synthesis of podophyllotoxin-naphthoquinone compounds using microwave-assisted three-component reactions is reported in this study. Novel podophyllotoxin-naphthoquinone derivatives with modification on ring E were synthesized. All the synthetic compounds were assessed in terms...
Autores principales: | Nguyen, Ha Thanh, Nguyen Thi, Quynh Giang, Nguyen Thi, Thu Ha, Thi, Phuong Hoang, Le-Nhat-Thuy, Giang, Dang Thi, Tuyet Anh, Le-Quang, Bao, Pham-The, Hai, Van Nguyen, Tuyen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361925/ https://www.ncbi.nlm.nih.gov/pubmed/36043070 http://dx.doi.org/10.1039/d2ra03312g |
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