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A CRISPR-based ultrasensitive assay detects attomolar concentrations of SARS-CoV-2 antibodies in clinical samples

CRISPR diagnostics are powerful tools for detecting nucleic acids but are generally not deployable for the detection of clinically important proteins. Here, we report an ultrasensitive CRISPR-based antibody detection (UCAD) assay that translates the detection of anti-SARS-CoV-2 antibodies into CRISP...

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Detalles Bibliográficos
Autores principales: Tang, Yanan, Song, Turun, Gao, Lu, Yin, Saifu, Ma, Ming, Tan, Yun, Wu, Lijuan, Yang, Yang, Wang, Yanqun, Lin, Tao, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361972/
https://www.ncbi.nlm.nih.gov/pubmed/35945418
http://dx.doi.org/10.1038/s41467-022-32371-4