A comprehensive in silico exploration of the impacts of missense variants on two different conformations of human pirin protein

BACKGROUND: Pirin, a member of the cupin superfamily, is an iron-binding non-heme protein. It acts as a coregulator of several transcription factors, especially the members of NFκB transcription factor family. Based on the redox state of its iron cofactor, it can assume two different conformations a...

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Detalles Bibliográficos
Autores principales: Khan, Auroni Semonti, Parvez, Nahid, Ahsan, Tamim, Shoily, Sabrina Samad, Sajib, Abu Ashfaqur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362109/
https://www.ncbi.nlm.nih.gov/pubmed/35967515
http://dx.doi.org/10.1186/s42269-022-00917-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362109/
https://www.ncbi.nlm.nih.gov/pubmed/35967515
http://dx.doi.org/10.1186/s42269-022-00917-7

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