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A comprehensive in silico exploration of the impacts of missense variants on two different conformations of human pirin protein
BACKGROUND: Pirin, a member of the cupin superfamily, is an iron-binding non-heme protein. It acts as a coregulator of several transcription factors, especially the members of NFκB transcription factor family. Based on the redox state of its iron cofactor, it can assume two different conformations a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362109/ https://www.ncbi.nlm.nih.gov/pubmed/35967515 http://dx.doi.org/10.1186/s42269-022-00917-7 |