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Lanmodulin peptides – unravelling the binding of the EF-Hand loop sequences stripped from the structural corset

Lanmodulin (LanM), a naturally lanthanide (Ln)-binding protein with a remarkable selectivity for Lns over Ca(ii) and affinities in the picomolar range, is an attractive target to address challenges in Ln separation. Why LanM has such a high selectivity is currently not entirely understood; both spec...

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Detalles Bibliográficos
Autores principales: Gutenthaler, Sophie M., Tsushima, Satoru, Steudtner, Robin, Gailer, Manuel, Hoffmann-Röder, Anja, Drobot, Björn, Daumann, Lena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362731/
https://www.ncbi.nlm.nih.gov/pubmed/36091973
http://dx.doi.org/10.1039/d2qi00933a