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GBA and APOE Impact Cognitive Decline in Parkinson’s Disease: A 10-Year Population-Based Study

BACKGROUND: Common genetic variance in apolipoprotein E (APOE), β-glucocerebrosidase (GBA), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) has been linked to cognitive decline in Parkinson’s disease (PD), although studies have yielded mixed esults. OBJECTIVES: To evaluate the effe...

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Detalles Bibliográficos
Autores principales: Szwedo, Aleksandra A., Dalen, Ingvild, Pedersen, Kenn Freddy, Camacho, Marta, Bäckström, David, Forsgren, Lars, Tzoulis, Charalampos, Winder-Rhodes, Sophie, Hudson, Gavin, Liu, Ganqiang, Scherzer, Clemens R., Lawson, Rachael A., Yarnall, Alison J., Williams-Gray, Caroline H., Macleod, Angus D., Counsell, Carl E., Tysnes, Ole-Bjørn, Alves, Guido, Maple-Grødem, Jodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362732/
https://www.ncbi.nlm.nih.gov/pubmed/35106798
http://dx.doi.org/10.1002/mds.28932