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Genotoxicity-Stimulated and CYLD-Driven Malignant Transformation

Oxidative stress, which can cause DNA damage, can both activate TNF-R1 directly in the absence of TNF stimulation and phosphorylate c-Abl, thus promoting its cytoplasmic translocation. Persistent cytoplasmic localization of c-Abl has been associated with cellular transformation. c-Abl phosphorylates...

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Detalles Bibliográficos
Autor principal: Erol, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362849/
https://www.ncbi.nlm.nih.gov/pubmed/35958947
http://dx.doi.org/10.2147/CMAR.S373557