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LILRB4, an immune checkpoint on myeloid cells

Leukocyte immunoglobulin-like receptor B4 (LILRB4) is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. By binding to ligands, LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory moti...

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Detalles Bibliográficos
Autores principales: Yang, Ting, Qian, Yixin, Liang, Xiaoting, Wu, Jianbo, Zou, Ming, Deng, Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362873/
https://www.ncbi.nlm.nih.gov/pubmed/35957669
http://dx.doi.org/10.1097/BS9.0000000000000109