Single-cell analysis of transcription factor regulatory networks reveals molecular basis for subtype-specific dysregulation in acute myeloid leukemia

Highly heterogeneous acute myeloid leukemia (AML) exhibits dysregulated transcriptional programs. Transcription factor (TF) regulatory networks underlying AML subtypes have not been elucidated at single-cell resolution. Here, we comprehensively mapped malignancy-related TFs activated in different AM...

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Detalles Bibliográficos
Autores principales: Sun, Ruixia, Sun, Lina, Xie, Xiaowei, Li, Xuan, Wu, Peng, Wang, Lu, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362874/
https://www.ncbi.nlm.nih.gov/pubmed/35957668
http://dx.doi.org/10.1097/BS9.0000000000000113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362874/
https://www.ncbi.nlm.nih.gov/pubmed/35957668
http://dx.doi.org/10.1097/BS9.0000000000000113

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