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Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A meta-analysis

INTRODUCTION: Cystic fibrosis (CF) is a hereditary autosomal recessive disorder caused by a range of mutations in the CF Transmembrane Conductance Regulator (CFTR) gene. This gene encodes the CFTR protein, which acts as a chloride channel activated by cyclic AMP (cAMP). This meta-analysis aimed to c...

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Detalles Bibliográficos
Autores principales: Darwish, Toqa, Al-Khulaifi, Azhar, Ali, Menatalla, Mowafy, Rana, Arredouani, Abdelilah, Doi, Suhail A., Emara, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362911/
https://www.ncbi.nlm.nih.gov/pubmed/35944004
http://dx.doi.org/10.1371/journal.pone.0272091