Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species

All tRNAs have numerous modifications, lack of which often results in growth defects in the budding yeast Saccharomyces cerevisiae and neurological or other disorders in humans. In S. cerevisiae, lack of tRNA body modifications can lead to impaired tRNA stability and decay of a subset of the hypomod...

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Detalles Bibliográficos
Autores principales: Tasak, Monika, Phizicky, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362929/
https://www.ncbi.nlm.nih.gov/pubmed/35901126
http://dx.doi.org/10.1371/journal.pgen.1010215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362929/
https://www.ncbi.nlm.nih.gov/pubmed/35901126
http://dx.doi.org/10.1371/journal.pgen.1010215

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