Hesperetin mitigates sorafenib-induced cardiotoxicity in mice through inhibition of the TLR4/NLRP3 signaling pathway

Sorafenib is an oral multi-kinase receptor inhibitor that targets various signaling pathways. It is used as the first line of treatment in advanced hepatocellular and renal cell carcinomas. Sorafenib was reported to induce cardiotoxicity due to myocyte necrosis. Hesperetin is a naturally occurring f...

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Detalles Bibliográficos
Autores principales: Zaafar, Dalia, Khalil, Heba M. A., Rasheed, Rabab Ahmed, Eltelbany, Rania Farag A., Zaitone, Sawsan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362940/
https://www.ncbi.nlm.nih.gov/pubmed/35944026
http://dx.doi.org/10.1371/journal.pone.0271631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362940/
https://www.ncbi.nlm.nih.gov/pubmed/35944026
http://dx.doi.org/10.1371/journal.pone.0271631

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