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Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes

Hepadnaviruses use extensively overlapping genes to expand their coding capacity, especially the precore/core genes encode the precore and core proteins with mostly identical sequences but distinct functions. The precore protein of the woodchuck hepatitis virus (WHV) is N-glycosylated, in contrast t...

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Detalles Bibliográficos
Autores principales: Hong, Xupeng, Menne, Stephan, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362955/
https://www.ncbi.nlm.nih.gov/pubmed/35901192
http://dx.doi.org/10.1371/journal.ppat.1010739