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Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq

Antibiotic resistance in the important opportunistic human pathogen Streptococcus pneumoniae is on the rise. This is particularly problematic in the case of the β-lactam antibiotic amoxicillin, which is the first-line therapy. It is therefore crucial to uncover targets that would kill or resensitize...

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Detalles Bibliográficos
Autores principales: Dewachter, Liselot, Dénéréaz, Julien, Liu, Xue, de Bakker, Vincent, Costa, Charlotte, Baldry, Mara, Sirard, Jean-Claude, Veening, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363119/
https://www.ncbi.nlm.nih.gov/pubmed/35748540
http://dx.doi.org/10.7554/eLife.75607