Positive feedback regulation of frizzled-7 expression robustly shapes a steep Wnt gradient in Xenopus heart development, together with sFRP1 and heparan sulfate

Secreted molecules called morphogens govern tissue patterning in a concentration-dependent manner. However, it is still unclear how reproducible patterning can be achieved with diffusing molecules, especially when that patterning concerns differentiation of thin tissues. Wnt is a morphogen that orga...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takayoshi, Kambayashi, Yuta, Otsuka, Yuta, Afouda, Boni A, Giuraniuc, Claudiu, Michiue, Tatsuo, Hoppler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363125/
https://www.ncbi.nlm.nih.gov/pubmed/35942683
http://dx.doi.org/10.7554/eLife.73818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363125/
https://www.ncbi.nlm.nih.gov/pubmed/35942683
http://dx.doi.org/10.7554/eLife.73818

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