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The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer

Nonsmall cell lung cancer (NSCLC) is a predominant subtype of lung cancer and accounts for over 80% of all lung cancer cases. The resistance to pemetrexed (PEM) is frequently occurred and severely affects the NSCLC therapy. Proteomic analysis of histones indicated that the histone deacetylase 1 (HDA...

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Detalles Bibliográficos
Autores principales: Jiang, Chuan, Liao, Jiangrong, Yang, Fang, Jiang, Ting, Zhang, Dan, Xin, Yuanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363190/
https://www.ncbi.nlm.nih.gov/pubmed/35958929
http://dx.doi.org/10.1155/2022/5049116