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Pharmacogenomics of Clozapine-induced agranulocytosis: a systematic review and meta-analysis

Although clozapine is the most effective pharmacotherapy for treatment-resistant schizophrenia, it is under-utilized, and initiation is often delayed. One reason is the occurrence of a potentially fatal adverse reaction, clozapine-induced agranulocytosis (CIA). Identifying genetic variations contrib...

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Detalles Bibliográficos
Autores principales:	Islam, Farhana, Hain, Daniel, Lewis, David, Law, Rebecca, Brown, Lisa C., Tanner, Julie-Anne, Müller, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363274/ https://www.ncbi.nlm.nih.gov/pubmed/35710824 http://dx.doi.org/10.1038/s41397-022-00281-9

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