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Resurrection of sildenafil: potential for Huntington’s Disease, too?
The phosphodiesterase-5 inhibitor sildenafil was postulated to reduce the risk for Alzheimer’s Disease. Since preclinical data revealed beneficial effects in Huntington’s Disease (HD), we now for the first time investigated effects of sildenafil in HD patients using the database ENROLL-HD. We demons...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363275/ https://www.ncbi.nlm.nih.gov/pubmed/35633374 http://dx.doi.org/10.1007/s00415-022-11196-7 |