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A previously unknown Argonaute 2 variant positively modulates the viability of melanoma cells

In malignant melanoma, a highly aggressive form of skin cancer, many microRNAs are aberrantly expressed contributing to tumorigenesis and progression. Further, deregulation of microRNA processing enzymes, like the miRNA-binding protein Argonaute 2, significantly impacts microRNA function. This study...

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Detalles Bibliográficos
Autores principales: Linck-Paulus, Lisa, Meißgeier, Tina, Pieger, Katharina, Horn, Anselm H. C., Matthies, Alexander, Fischer, Stefan, Meister, Gunter, Sticht, Heinrich, Kappelmann-Fenzl, Melanie, Bosserhoff, Anja K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363364/
https://www.ncbi.nlm.nih.gov/pubmed/35943635
http://dx.doi.org/10.1007/s00018-022-04496-8