Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones cultivated at high cell density

The growing interest in the use of lentiviral vectors (LVs) for various applications has created a strong demand for large quantities of vectors. To meet the increased demand, we developed a high cell density culture process for production of LV using stable producer clones generated from HEK293 cel...

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Detalles Bibliográficos
Autores principales: Shen, Chun Fang, Tremblay, Sonia, Sabourin-Poirier, Catherine, Burney, Elodie, Broussau, Sophie, Manceur, Aziza, Rodenbrock, Anja, Voyer, Robert, Loignon, Martin, Ansorge, Sven, Gilbert, Rénald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363386/
https://www.ncbi.nlm.nih.gov/pubmed/35758994
http://dx.doi.org/10.1007/s00449-022-02737-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363386/
https://www.ncbi.nlm.nih.gov/pubmed/35758994
http://dx.doi.org/10.1007/s00449-022-02737-5

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