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Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones cultivated at high cell density
The growing interest in the use of lentiviral vectors (LVs) for various applications has created a strong demand for large quantities of vectors. To meet the increased demand, we developed a high cell density culture process for production of LV using stable producer clones generated from HEK293 cel...
Autores principales: | Shen, Chun Fang, Tremblay, Sonia, Sabourin-Poirier, Catherine, Burney, Elodie, Broussau, Sophie, Manceur, Aziza, Rodenbrock, Anja, Voyer, Robert, Loignon, Martin, Ansorge, Sven, Gilbert, Rénald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363386/ https://www.ncbi.nlm.nih.gov/pubmed/35758994 http://dx.doi.org/10.1007/s00449-022-02737-5 |
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