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Synthesis of bioactive (1→6)-β-glucose branched poly-amido-saccharides that stimulate and induce M1 polarization in macrophages

β-Glucans are of significant interest due to their potent antitumor and immunomodulatory activities. Nevertheless, the difficulty in purification, structural heterogenicity, and limited solubility impede the development of structure-property relationships and translation to therapeutic applications....

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Detalles Bibliográficos
Autores principales: Xiao, Ruiqing, Zeng, Jialiu, Bressler, Eric M., Lu, Wei, Grinstaff, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363418/
https://www.ncbi.nlm.nih.gov/pubmed/35945224
http://dx.doi.org/10.1038/s41467-022-32346-5