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Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

Characterising associations between the methylome, proteome and phenome may provide insight into biological pathways governing brain health. Here, we report an integrated DNA methylation and phenotypic study of the circulating proteome in relation to brain health. Methylome-wide association studies...

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Detalles Bibliográficos
Autores principales: Gadd, Danni A., Hillary, Robert F., McCartney, Daniel L., Shi, Liu, Stolicyn, Aleks, Robertson, Neil A., Walker, Rosie M., McGeachan, Robert I., Campbell, Archie, Xueyi, Shen, Barbu, Miruna C., Green, Claire, Morris, Stewart W., Harris, Mathew A., Backhouse, Ellen V., Wardlaw, Joanna M., Steele, J. Douglas, Oyarzún, Diego A., Muniz-Terrera, Graciela, Ritchie, Craig, Nevado-Holgado, Alejo, Chandra, Tamir, Hayward, Caroline, Evans, Kathryn L., Porteous, David J., Cox, Simon R., Whalley, Heather C., McIntosh, Andrew M., Marioni, Riccardo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363452/
https://www.ncbi.nlm.nih.gov/pubmed/35945220
http://dx.doi.org/10.1038/s41467-022-32319-8