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Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health
Characterising associations between the methylome, proteome and phenome may provide insight into biological pathways governing brain health. Here, we report an integrated DNA methylation and phenotypic study of the circulating proteome in relation to brain health. Methylome-wide association studies...
Autores principales: | Gadd, Danni A., Hillary, Robert F., McCartney, Daniel L., Shi, Liu, Stolicyn, Aleks, Robertson, Neil A., Walker, Rosie M., McGeachan, Robert I., Campbell, Archie, Xueyi, Shen, Barbu, Miruna C., Green, Claire, Morris, Stewart W., Harris, Mathew A., Backhouse, Ellen V., Wardlaw, Joanna M., Steele, J. Douglas, Oyarzún, Diego A., Muniz-Terrera, Graciela, Ritchie, Craig, Nevado-Holgado, Alejo, Chandra, Tamir, Hayward, Caroline, Evans, Kathryn L., Porteous, David J., Cox, Simon R., Whalley, Heather C., McIntosh, Andrew M., Marioni, Riccardo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363452/ https://www.ncbi.nlm.nih.gov/pubmed/35945220 http://dx.doi.org/10.1038/s41467-022-32319-8 |
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