Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer

Detection of driver gene mutations is important in advanced NSCLC. The cobas EGFR mutation test is a mutant allele-specific real-time PCR assay with limitation owing to its primer design. Next-generation sequencing-based assay has a higher mutation detection coverage; however, its clinical impact re...

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Detalles Bibliográficos
Autores principales: Shen, Chia-I, Chiang, Chi-Lu, Shiao, Tsu-Hui, Luo, Yung-Hung, Chao, Heng-Sheng, Huang, Hsu-Ching, Chiu, Chao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363455/
https://www.ncbi.nlm.nih.gov/pubmed/35945330
http://dx.doi.org/10.1038/s41598-022-17394-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363455/
https://www.ncbi.nlm.nih.gov/pubmed/35945330
http://dx.doi.org/10.1038/s41598-022-17394-7

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