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Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer
Detection of driver gene mutations is important in advanced NSCLC. The cobas EGFR mutation test is a mutant allele-specific real-time PCR assay with limitation owing to its primer design. Next-generation sequencing-based assay has a higher mutation detection coverage; however, its clinical impact re...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363455/ https://www.ncbi.nlm.nih.gov/pubmed/35945330 http://dx.doi.org/10.1038/s41598-022-17394-7 |