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MicroRNA-379-5p regulates free cholesterol accumulation and relieves diet induced-liver damage in db/db mice via STAT1/HMGCS1 axis

Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH). MicroRNA (miR)-379-5p has been reported to play regulato...

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Detalles Bibliográficos
Autores principales: Dong, Yunxia, Yu, Chuwei, Ma, Ningning, Xu, Xiaoding, Wu, Qian, Lu, Henglei, Gong, Likun, Chen, Jing, Ren, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363541/
https://www.ncbi.nlm.nih.gov/pubmed/35945406
http://dx.doi.org/10.1186/s43556-022-00089-w