Multidrug-resistant Pseudomonas aeruginosa is predisposed to lasR mutation through up-regulated activity of efflux pumps in non-cystic fibrosis bronchiectasis patients

BACKGROUND: Multidrug-resistant (MDR) Pseudomonas aeruginosa is a frequent opportunistic pathogen that causes significant mortality in patients with non-cystic fibrosis bronchiectasis (NCFB). Although the quorum sensing (QS) system is a potential target for treatment, lasR mutants that present with...

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Detalles Bibliográficos
Autores principales: Ding, Fengming, Han, Lei, Xue, Yishu, Yang, Iris Tingshiuan, Fan, Xinxin, Tang, Rong, Zhang, Chen, Zhu, Miao, Tian, Xue, Shao, Ping, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363577/
https://www.ncbi.nlm.nih.gov/pubmed/35967851
http://dx.doi.org/10.3389/fcimb.2022.934439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363577/
https://www.ncbi.nlm.nih.gov/pubmed/35967851
http://dx.doi.org/10.3389/fcimb.2022.934439

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