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Multidrug-resistant Pseudomonas aeruginosa is predisposed to lasR mutation through up-regulated activity of efflux pumps in non-cystic fibrosis bronchiectasis patients

BACKGROUND: Multidrug-resistant (MDR) Pseudomonas aeruginosa is a frequent opportunistic pathogen that causes significant mortality in patients with non-cystic fibrosis bronchiectasis (NCFB). Although the quorum sensing (QS) system is a potential target for treatment, lasR mutants that present with...

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Detalles Bibliográficos
Autores principales:	Ding, Fengming, Han, Lei, Xue, Yishu, Yang, Iris Tingshiuan, Fan, Xinxin, Tang, Rong, Zhang, Chen, Zhu, Miao, Tian, Xue, Shao, Ping, Zhang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363577/ https://www.ncbi.nlm.nih.gov/pubmed/35967851 http://dx.doi.org/10.3389/fcimb.2022.934439

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