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eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon production

Active hypusine-modified initiation elongation factor 5A is critical for cell proliferation and differentiation, embryonic development, and innate immune response of macrophages to bacterial infection. Here, we demonstrate that both virus infection and double-stranded RNA viral mimic stimulation ind...

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Detalles Bibliográficos
Autores principales: Seoane, Rocío, Llamas-González, Yessica Y., Vidal, Santiago, El Motiam, Ahmed, Bouzaher, Yanis Hichem, Fonseca, Danae, Farrás, Rosa, García-Sastre, Adolfo, González-Santamaría, José, Rivas, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363599/
https://www.ncbi.nlm.nih.gov/pubmed/35967877
http://dx.doi.org/10.3389/fcimb.2022.960138