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Reduced Expression of TMEM16A Impairs Nitric Oxide-Dependent Cl(−) Transport in Retinal Amacrine Cells
Postsynaptic cytosolic Cl(−) concentration determines whether GABAergic and glycinergic synapses are inhibitory or excitatory. We have shown that nitric oxide (NO) initiates the release of Cl(−) from acidic internal stores into the cytosol of retinal amacrine cells (ACs) thereby elevating cytosolic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363626/ https://www.ncbi.nlm.nih.gov/pubmed/35966201 http://dx.doi.org/10.3389/fncel.2022.937060 |