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Reduced Expression of TMEM16A Impairs Nitric Oxide-Dependent Cl(−) Transport in Retinal Amacrine Cells

Postsynaptic cytosolic Cl(−) concentration determines whether GABAergic and glycinergic synapses are inhibitory or excitatory. We have shown that nitric oxide (NO) initiates the release of Cl(−) from acidic internal stores into the cytosol of retinal amacrine cells (ACs) thereby elevating cytosolic...

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Detalles Bibliográficos
Autores principales: Rodriguez, Tyler Christopher, Zhong, Li, Simpson, Hailey, Gleason, Evanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363626/
https://www.ncbi.nlm.nih.gov/pubmed/35966201
http://dx.doi.org/10.3389/fncel.2022.937060