Onco-immunomodulatory properties of pharmacological interference with RAS-RAF-MEK-ERK pathway hyperactivation

Hyperactivation of the RAS-RAF-MEK-ERK cascade - a mitogen-activated protein kinase pathway – has a well-known association with oncogenesis of leading tumor entities, including non-small cell lung cancer, colorectal carcinoma, pancreatic ductal adenocarcinoma, and malignant melanoma. Increasing evid...

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Detalles Bibliográficos
Autores principales: Avery, Thomas Yul, Köhler, Natalie, Zeiser, Robert, Brummer, Tilman, Ruess, Dietrich Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363660/
https://www.ncbi.nlm.nih.gov/pubmed/35965494
http://dx.doi.org/10.3389/fonc.2022.931774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363660/
https://www.ncbi.nlm.nih.gov/pubmed/35965494
http://dx.doi.org/10.3389/fonc.2022.931774

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