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Ciliary Neurotrophic Factor Derived From Astrocytes Protects Retinal Ganglion Cells Through PI3K/AKT, JAK/STAT, and MAPK/ERK Pathways

PURPOSE: The purpose of this study was to investigate the roles of ciliary neurotrophic factor (CNTF) on the protective effects of astrocytes on retinal ganglion cells (RGCs). METHODS: Primary RGCs were isolated from neonatal rats. Oxidative stress was induced, and the effects of co-culture with ast...

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Detalles Bibliográficos
Autores principales: Lee, Kwanghyun, Choi, Jin-Ok, Hwang, Ahreum, Bae, Hyoung Won, Kim, Chan Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363680/
https://www.ncbi.nlm.nih.gov/pubmed/35925584
http://dx.doi.org/10.1167/iovs.63.9.4