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Enhanced hippocampal neurogenesis mediated by PGC-1α-activated OXPHOS after neonatal low-dose Propofol exposure

BACKGROUND: Developing brain is highly plastic and can be easily affected. Growing pediatric usage of anesthetics during painless procedures has raised concerns about the effect of low-dose anesthetics on neurodevelopment. It is urgent to ascertain the neuronal effect of low-dose Propofol, a widely...

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Detalles Bibliográficos
Autores principales: Chen, Keyu, Lu, Dihan, Yang, Xiaoyu, Zhou, Rui, Lan, Liangtian, Wu, Yan, Wang, Chen, Xu, Xuanxian, Jiang, Mei Hua, Wei, Ming, Feng, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363786/
https://www.ncbi.nlm.nih.gov/pubmed/35966788
http://dx.doi.org/10.3389/fnagi.2022.925728