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In rheumatoid arthritis inflamed joints share dominant patient-specific B-cell clones

BACKGROUND: In patients with rheumatoid arthritis (RA) different joints were shown to share the same dominant T-cell clones, suggesting shared characteristics of the inflammatory process and indicating that strategies to selectively target the antigen receptor might be feasible. Since T- and B-lymph...

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Detalles Bibliográficos
Autores principales: Musters, Anne, Balzaretti, Giulia, van Schaik, Barbera D. C., Jongejan, Aldo, van der Weele, Linda, Tas, Sander W., van Kampen, Antoine H. C., de Vries, Niek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363889/
https://www.ncbi.nlm.nih.gov/pubmed/35967291
http://dx.doi.org/10.3389/fimmu.2022.915687