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RecA and RecB: probing complexes of DNA repair proteins with mitomycin C in live Escherichia coli with single-molecule sensitivity

The RecA protein and RecBCD complex are key bacterial components for the maintenance and repair of DNA. RecBCD is a helicase-nuclease that uses homologous recombination to resolve double-stranded DNA breaks. It also facilitates coating of single-stranded DNA with RecA to form RecA filaments, a vital...

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Detalles Bibliográficos
Autores principales: Payne-Dwyer, Alex L., Syeda, Aisha H., Shepherd, Jack W., Frame, Lewis, Leake, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363994/
https://www.ncbi.nlm.nih.gov/pubmed/35946163
http://dx.doi.org/10.1098/rsif.2022.0437