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Ion channel model reduction using manifold boundaries

Mathematical models of voltage-gated ion channels are used in basic research, industrial and clinical settings. These models range in complexity, but typically contain numerous variables representing the proportion of channels in a given state, and parameters describing the voltage-dependent rates o...

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Detalles Bibliográficos
Autores principales: Whittaker, Dominic G., Wang, Jiahui, Shuttleworth, Joseph G., Venkateshappa, Ravichandra, Kemp, Jacob M., Claydon, Thomas W., Mirams, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363999/
https://www.ncbi.nlm.nih.gov/pubmed/35946166
http://dx.doi.org/10.1098/rsif.2022.0193