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Ion channel model reduction using manifold boundaries
Mathematical models of voltage-gated ion channels are used in basic research, industrial and clinical settings. These models range in complexity, but typically contain numerous variables representing the proportion of channels in a given state, and parameters describing the voltage-dependent rates o...
Autores principales: | Whittaker, Dominic G., Wang, Jiahui, Shuttleworth, Joseph G., Venkateshappa, Ravichandra, Kemp, Jacob M., Claydon, Thomas W., Mirams, Gary R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363999/ https://www.ncbi.nlm.nih.gov/pubmed/35946166 http://dx.doi.org/10.1098/rsif.2022.0193 |
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