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In vitro single molecule and bulk phase studies reveal the AP-1 transcription factor cFos binds to DNA without its partner cJun

The AP-1 transcription factor family crucially regulates progression of the cell cycle, as well as playing roles in proliferation, differentiation, and the stress response. The two best described AP-1 family members, cFos and cJun, are known to dimerize to form a functional AP-1 heterodimer that bin...

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Detalles Bibliográficos
Autores principales: Leech, James T., Brennan, Andrew, Don, Nicola A., Mason, Jody M., Kad, Neil M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364023/
https://www.ncbi.nlm.nih.gov/pubmed/35787376
http://dx.doi.org/10.1016/j.jbc.2022.102229