Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation

Lysosomal storage diseases result in various developmental and physiological complications, including cachexia. To study the causes for the negative energy balance associated with cachexia, we assessed the impact of sulfamidase deficiency and heparan sulfate storage on energy homeostasis and metabol...

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Detalles Bibliográficos
Autores principales: Tillo, Miguel, Lamanna, William C., Dwyer, Chrissa A., Sandoval, Daniel R., Pessentheiner, Ariane R., Al-Azzam, Norah, Sarrazin, Stéphane, Gonzales, Jon C., Kan, Shih-Hsin, Andreyev, Alexander Y., Schultheis, Nicholas, Thacker, Bryan E., Glass, Charles A., Dickson, Patricia I., Wang, Raymond Y., Selleck, Scott B., Esko, Jeffrey D., Gordts, Philip L.S.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364035/
https://www.ncbi.nlm.nih.gov/pubmed/35750212
http://dx.doi.org/10.1016/j.jbc.2022.102159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364035/
https://www.ncbi.nlm.nih.gov/pubmed/35750212
http://dx.doi.org/10.1016/j.jbc.2022.102159

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