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Chronic hyperinsulinemia promotes human hepatocyte senescence

OBJECTIVE: Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells have been identified in multiple tissues in different metabolic and other aging-related diseases. Recently, several human and mous...

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Detalles Bibliográficos
Autores principales: Baboota, Ritesh K., Spinelli, Rosa, Erlandsson, Malin C., Brandao, Bruna B., Lino, Marsel, Yang, Hong, Mardinoglu, Adil, Bokarewa, Maria I., Boucher, Jeremie, Kahn, C. Ronald, Smith, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364104/
https://www.ncbi.nlm.nih.gov/pubmed/35872305
http://dx.doi.org/10.1016/j.molmet.2022.101558