A UHM–ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing

During spliceosome assembly, the 3′ splice site is recognized by sequential U2AF2 complexes, first with Splicing Factor 1 (SF1) and second by the SF3B1 subunit of the U2 small nuclear ribonuclear protein particle. The U2AF2–SF1 interface is well characterized, comprising a U2AF homology motif (UHM)...

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Detalles Bibliográficos
Autores principales: Galardi, Justin W., Bela, Victoria N., Jeffery, Nazish, He, Xueyang, Glasser, Eliezra, Loerch, Sarah, Jenkins, Jermaine L., Pulvino, Mary J., Boutz, Paul L., Kielkopf, Clara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364107/
https://www.ncbi.nlm.nih.gov/pubmed/35780835
http://dx.doi.org/10.1016/j.jbc.2022.102224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364107/
https://www.ncbi.nlm.nih.gov/pubmed/35780835
http://dx.doi.org/10.1016/j.jbc.2022.102224

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