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Design, synthesis and biological evaluation of benzo-[d]-imidazo-[2,1-b]-thiazole and imidazo-[2,1-b]-thiazole carboxamide triazole derivatives as antimycobacterial agents

In the search for new anti-mycobacterial agents, we revealed the importance of imidazo-[2,1-b]-thiazole and benzo-[d]-imidazo-[2,1-b]-thiazole carboxamide derivatives. We designed, in silico ADMET predicted and synthesized four series of novel imidazo-[2,1-b]-thiazole and benzo-[d]-imidazo-[2,1-b]-t...

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Detalles Bibliográficos
Autores principales: Chitti, Surendar, Van Calster, Kevin, Cappoen, Davie, Nandikolla, Adinarayana, Khetmalis, Yogesh Mahadu, Cos, Paul, Kumar, Banoth Karan, Murugesan, Sankaranarayanan, Gowri Chandra Sekhar, Kondapalli Venkata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364363/
https://www.ncbi.nlm.nih.gov/pubmed/36105967
http://dx.doi.org/10.1039/d2ra03318f