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Predicting RNA distance-based contact maps by integrated deep learning on physics-inferred secondary structure and evolutionary-derived mutational coupling

MOTIVATION: Recently, AlphaFold2 achieved high experimental accuracy for the majority of proteins in Critical Assessment of Structure Prediction (CASP 14). This raises the hope that one day, we may achieve the same feat for RNA structure prediction for those structured RNAs, which is as fundamentall...

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Detalles Bibliográficos
Autores principales: Singh, Jaswinder, Paliwal, Kuldip, Litfin, Thomas, Singh, Jaspreet, Zhou, Yaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364379/
https://www.ncbi.nlm.nih.gov/pubmed/35751593
http://dx.doi.org/10.1093/bioinformatics/btac421