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Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4(+) T-cell migration in SLE

OBJECTIVE: SLE is an autoimmune disease with a complex pathogenesis. T-cell infiltration into organs contributes to inflammation and organ damage in SLE. Recently, G-protein signalling modulator 2 (GPSM2) has been shown to be implicated in T-cell migration. METHODS: We analysed the expression levels...

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Detalles Bibliográficos
Autores principales: Esser, Ruth L, Brück, Carolin, Thiele, Jan, Golumba-Nagy, Viktoria, Meyer, Anja, Steinbach-Knödgen, Eva, Yan, Shuaifeng, tho Pesch, Carola, Stahl, David, Schiller, Joanna, Kofler, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364394/
https://www.ncbi.nlm.nih.gov/pubmed/35940821
http://dx.doi.org/10.1136/lupus-2022-000742