Mechanistic Studies on the Stereoselectivity of FFAR1 Modulators

[Image: see text] Free fatty acid receptor 1 (FFAR1) is a potential therapeutic target for the treatment of type 2 diabetes (T2D). It has been validated that agonists targeting FFAR1 can achieve the initial therapeutic endpoints of T2D, and the epimer agonists (R,S) AM-8596 can activate FFAR1 differ...

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Detalles Bibliográficos
Autores principales: Teng, Dan, Zhou, Yang, Tang, Yun, Liu, Guixia, Tu, Yaoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364411/
https://www.ncbi.nlm.nih.gov/pubmed/35877470
http://dx.doi.org/10.1021/acs.jcim.2c00417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364411/
https://www.ncbi.nlm.nih.gov/pubmed/35877470
http://dx.doi.org/10.1021/acs.jcim.2c00417

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