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Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice

BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes local bone erosion and systemic osteoporosis. Harpagoside (HAR), an iridoid glycoside, has various pharmacological effects on pain, arthritis, and inflammation. Our previous study suggests that HAR is more...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Young, Cheon, Yoon-Hee, Ahn, Sung-Jun, Kwak, Sung Chul, Chung, Chong Hyuk, Lee, Chang Hoon, Lee, Myeung Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364518/
https://www.ncbi.nlm.nih.gov/pubmed/35948905
http://dx.doi.org/10.1186/s12906-022-03694-y