CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a dismal prognosis. Although combined treatment with gemcitabine and albumin-bound paclitaxel has improved the prognosis of PDAC, both intrinsic and acquired chemoresistance remain as severe hurtles towards improved pro...

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Detalles Bibliográficos
Autores principales: Zeng, Siyuan, Lan, Bin, Ren, Xiaofan, Zhang, Shuman, Schreyer, Daniel, Eckstein, Markus, Yang, Hai, Britzen-Laurent, Nathalie, Dahl, Andreas, Mukhopadhyay, Debabrata, Chang, David, Kutschick, Isabella, Pfeffer, Susanne, Bailey, Peter, Biankin, Andrew, Grützmann, Robert, Pilarsky, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364549/
https://www.ncbi.nlm.nih.gov/pubmed/35945614
http://dx.doi.org/10.1186/s13046-022-02443-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364549/
https://www.ncbi.nlm.nih.gov/pubmed/35945614
http://dx.doi.org/10.1186/s13046-022-02443-w

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